HSP90 is a group of special proteins synthesized and activated under heat stress.HSP90 is one of the most active molecular chaperones in cells, which plays an important role in cell survival under physiological, pathological and stress conditions. When the stress reaction occurs, HSP90 changes its conformation due to environmental stimulation to ensure proper folding of protein and prevent its nonspecific aggregation, thus maintaining the normal activity of cells. In the process of tumor formation, a large number of HSP90 protein is expressed 2-10 times more than that of normal cells. As a molecular chaperone, Hsp90 plays a role in regulating and stabilizing the growth and metabolism of tumor cells. It can be seen that HSP90 may be one of the biomarkers of tumor diagnosis, so the detection of serum Hsp90 can be used as a method of tumor auxiliary diagnosis.
|HSP90 Monoclonal Antibody|