Almost all biopharmaceutical products can cause a certain anti-drug antibody (ADA) response, that is, immune response.
In the process of pharmacokinetic study, the evaluation of anti-drug antibodies (ADA) has become a prominent problem. ADA may have a significant impact on the results of PK research. The preparation of anti-drug antibodies is indispensable for the detection of ADAs.
After immunization, the serum titer was more than 500,000 times dilution.
Specific recognition of Fab, no cross-reaction with human.
Can carry out pre-clinical PD/PK research services. To provide reliable data support for clinical trials of antibody drugs.
Provide one-stop services, including antigen design, antibody preparation and high throughput antibody production.
| stage 1:establishment and validation of Fab animal immunization and screening method | ||
| customer supply | delivery standard | cycle |
| 100 mg full-length antibody, purity > 95% (We prepared 20mg Fab by enzymatic digestion and purification) |
· indirect ELISA Detection Report | 2-3 months |
| stage 2:affinity purification of anti-Fab polyclonal antibody | ||
| customer supply | delivery standard | cycle |
| about 20mg hlgG of purification | · M2 Report · purification of Fab from all antisera |
1-2weeks |
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